由Gil Grissom领导的拉斯维加斯警局犯罪鉴证科夜班组的任务是深入案发现场寻找种种蛛丝马迹，并利用最先进的科技手段，把表面上没有任何联系、没有意义的线索拼凑成不可辩驳的证据，抽丝剥茧重组案情，让犯罪分子无处可逃…… 　　这套剧集展现了大量前沿尖端的高科技侦破技术：弹道学、犯罪危险因子学、法医毒

Russell and Finlay must confront a serial killer case from their past while working in Seattle when a copycat killer suddenly emerges in Las Vegas.

Russell and Finlay must confront a serial killer case from their past while working in Seattle when a copycat killer suddenly emerges in Las Vegas.

Russell and Finlay must confront a serial killer case from their past while working in Seattle when a copycat killer suddenly emerges in Las Vegas.

Russell and Finlay must confront a serial killer case from their past while working in Seattle when a copycat killer suddenly emerges in Las Vegas.

CBS的秋季时间表透露了CSI的最终命运：将推出一个2小时的电视电影作为大结局，元老级角色将回归，包括“葛瑞森”威廉·彼德森、“凯瑟琳”玛格·海根柏格。大结局将于9月27日播出，然后《网络犯罪调查(CSI:Cyber)》第二季接档。